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The BPDF provides public and private sector clients with early manufacturing services from strain development and optimization to final bulk production under current Good Manufacturing Practices.


The Biological Process Development Facility has a three-fold mission defining our commitment to student education and quality improvement. Read the entire mission.


Originally called the UNL Fermentation Facility, the BPDF was founded in 1990 by the UNL Food Processing Center and the UNL Center for Biotechnology to meet the fermentation needs of UNL. Read more about our history.


An $11.2 million Phase I/II cGMP pilot plant was completed on Dec 31, 2008. Read more.

The BPDF is:

-A leading expert in the recombinant expression system (Pichia pastoris ) used to express the Botulinum vaccines.

-One of the few University facilities working in the area of recombinant proteins.

-Focused on Phase I/II clinical material, allowing rapid development of new processes and production of therapeutic proteins.

  Othmer Hall on UNL's City Campus